Like most people, I brush my teeth daily—usually more than once—which means I’ve tried my fair share of toothpaste brands over the years. Toothpaste is one of those personal care items where preferences can vary widely, so when I create lists like this, I generally avoid reviewing or ranking them. Instead, I focus on researching the most trusted, best-selling brands Americans use and rely on. I’ve personally used some of these products listed below, as you have, but certainly not all of them. However, my goal isn’t to tell you what’s “better” but to share a researched list that helps people find new brands that better fit their needs and lifestyles.
1. Crest Toothpaste
Known as America’s highest-rated toothpaste brand, Crest is trusted for its effective formulas and wide range of products tailored to different dental needs. Crest offers options for the whole family, from cavity protection to advanced whitening. Their specialized lines, like Gum Detoxify and 3D White, cater to those focused on gum health or a brighter smile. With a longstanding reputation and innovations in oral care, Crest is a reliable choice for anyone looking for proven results in their daily dental routine.
2. Colgate Toothpaste
Ranked as the second-best brand in the U.S. for sales and ratings, Colgate is a household name synonymous with reliable oral care. Offering products for cavity prevention, gum health, sensitivity, and whitening, Colgate covers a broad spectrum of needs. Their Total line, designed for all-around protection, is particularly popular. Known for its affordability and accessibility, Colgate appeals to individuals and families seeking trusted, effective toothpaste that’s easy to find and consistently delivers on quality.
3. Sensodyne Toothpaste
As America’s third-best toothpaste brand, Sensodyne has been my personal go-to for over 15 years. It’s specially formulated for individuals with sensitive teeth, providing relief while strengthening enamel. Beyond sensitivity, Sensodyne offers protection against cavities and supports overall oral health. Options like Pronamel for enamel care and Rapid Relief for immediate sensitivity reduction are ideal for those prioritizing comfort and protection without compromising comprehensive dental benefits.
4. Boka Toothpaste
Boka toothpaste combines modern science with natural ingredients to promote long-term oral health. It features nano-hydroxyapatite, a fluoride alternative that strengthens enamel and reduces sensitivity. Free from artificial flavors, parabens, and sulfates, Boka is ideal for individuals seeking a clean, non-toxic toothpaste without compromising effectiveness. Its gentle formula appeals to those with sensitivity concerns, while its focus on enamel restoration makes it a strong choice for overall dental care.
5. Arm & Hammer Toothpaste
Arm & Hammer toothpaste combines the cleaning power of baking soda with fluoride for effective cavity prevention and whitening. Known for its natural, gentle cleaning properties, this brand is ideal for individuals looking for a toothpaste that neutralizes acids and promotes healthier gums. With options like Peroxicare for deep cleaning and Essentials for natural care, Arm & Hammer caters to those who value simple yet effective oral hygiene solutions focusing on long-term dental health.
6. Tom’s of Maine Toothpaste
Tom’s of Maine is a trusted brand for those seeking natural, eco-friendly oral care. Their fluoride and fluoride-free options are crafted with sustainably sourced ingredients, free from artificial flavors, colors, or preservatives. Popular among individuals looking to avoid harsh chemicals, Tom’s offers formulas for whitening, sensitivity, and cavity protection. With its environmental and social responsibility commitment, this brand appeals to health-conscious consumers who prioritize effective oral care and sustainable practices.
7. Hello Toothpaste
Hello Toothpaste offers a fresh approach to oral care, focusing on clean, natural ingredients and innovative formulas. Free from artificial sweeteners, dyes, and sulfates, Hello caters to individuals seeking a healthier, eco-conscious option. With varieties like charcoal for whitening and hemp seed oil for soothing care, Hello meets a wide range of needs. This brand’s playful packaging and commitment to cruelty-free, vegan products make it a popular choice for younger users and families.
8. Davids Fluoride Toothpaste
David’s fluoride toothpaste is crafted with natural ingredients and focuses on sustainability. Its fluoride formula supports enamel strength and cavity prevention while being free from artificial flavors, colors, and preservatives. Made in the USA, Davids is ideal for individuals seeking premium toothpaste that prioritizes effectiveness and environmental responsibility. The recyclable metal tube and commitment to cruelty-free practices make it an excellent option for eco-conscious consumers who want a blend of performance and sustainability.
9. Aquafresh Toothpaste
Aquafresh toothpaste is recognized for its triple-action formula that cleans, strengthens, and protects. The brand’s signature red, white, and blue stripes symbolize its focus on freshness, enamel care, and cavity prevention. Popular for its affordability and effectiveness, Aquafresh offers a range of products tailored to various needs, including whitening and kids’ formulas. Its balanced approach to oral care makes it a practical choice for families looking for a reliable, everyday toothpaste that delivers all-around benefits.
10. Parodontax Toothpaste
Parodontax toothpaste specializes in gum health, making it an excellent choice for individuals with bleeding gums or periodontal concerns. Its clinically proven formula helps reduce plaque and promote healthier gums while preventing cavities. With fluoride to strengthen enamel and a focus on improving oral health, Parodontax is ideal for those looking to address specific gum issues. The brand’s unique taste and targeted benefits cater to individuals prioritizing advanced care for their gums and overall dental hygiene.
11. Burt’s Bees Toothpaste
Burt’s Bees toothpaste combines natural ingredients with adequate oral care benefits. Free from artificial sweeteners, flavors, and preservatives, it offers options for whitening, cavity prevention, and enamel care. With responsibly sourced ingredients and recyclable packaging, Burt’s Bees is an excellent choice for those seeking eco-friendly and health-conscious products. Its gentle yet effective formulas cater to individuals who prioritize natural solutions while maintaining a focus on oral health.
12. Lumineux Toothpaste
Lumineux toothpaste focuses on non-toxic whitening and oral health, using natural ingredients that avoid harsh chemicals. Free from peroxide and artificial additives, it is ideal for individuals with sensitivity concerns or those seeking a gentler approach to whitening. The brand’s products promote balanced oral microbiomes, making it an excellent option for holistic dental care. Lumineux appeals to those who value natural, science-backed alternatives that deliver noticeable results without compromising safety.
13. Dr. Bronner’s Toothpaste
Dr. Bronner’s toothpaste is known for its simple, organic ingredients and dedication to sustainable practices. Free from fluoride, artificial flavors, and synthetic detergents, it uses coconut oil and baking soda to promote a healthy, clean mouth. Dr. Bronner’s vegan, cruelty-free formula is perfect for individuals seeking a natural, eco-conscious alternative to conventional toothpaste. Its commitment to fair trade and sustainability also resonates with those prioritizing ethical consumer choices.
14. Himalaya Toothpaste
Himalaya toothpaste is crafted with herbal and plant-based ingredients to provide natural care for oral health. Known for its fluoride-free options, it offers benefits like plaque removal, gum care, and fresh breath using ingredients such as neem and pomegranate. Ideal for those seeking gentle yet effective toothpaste without harsh chemicals, Himalaya appeals to individuals focused on natural remedies for maintaining healthy teeth and gums.
15. Weleda Toothpaste
Weleda toothpaste emphasizes natural oral care with its plant-based, fluoride-free formulations. Using ingredients like calendula, ratanhia, and myrrh, Weleda products are designed to support gum health, remove plaque, and freshen your breath. This brand is well-suited for those seeking eco-conscious options that prioritize gentle, holistic dental care. With its commitment to sustainability and minimal processing, Weleda is an excellent choice for individuals focused on ethical and natural solutions.
16. Orajel Toothpaste
Orajel toothpaste is best known for its targeted relief of oral discomfort, including toothaches and gum sensitivity. In addition to its pain-relief focus, Orajel offers products designed for children, with cavity protection and fluoride-based formulas to help build strong enamel. This brand is an excellent choice for families and individuals seeking fast, effective solutions for sensitive teeth or beginner-friendly toothpaste for kids transitioning to independent brushing.
17. Opalescence Teeth Toothpaste
Opalescence Teeth toothpaste is designed for advanced whitening, protecting enamel, and preventing cavities. Its gentle formula contains fluoride and potassium nitrate, making it suitable for individuals with sensitivity concerns. Commonly recommended by dental professionals, it helps maintain results from teeth-whitening treatments. Ideal for those seeking a bright smile without compromising oral health, Opalescence appeals to anyone focused on aesthetics and comprehensive dental care.
18. Auromere Herbal Toothpaste
Auromere Herbal toothpaste combines Ayurvedic principles with natural ingredients to support oral health. Featuring neem, licorice root, and 23 botanical extracts, it promotes gum health, fights plaque, and freshens breath. Free from fluoride, artificial sweeteners, and harsh chemicals, it’s well-suited for individuals looking for a holistic approach to dental care. Auromere’s eco-friendly packaging and natural focus make it a favorite among those who value environmentally conscious and herbal-based products.
19. Pepsodent Toothpaste
Pepsodent toothpaste is known for its classic cavity-fighting formula and affordable pricing. Enriched with fluoride, it helps strengthen enamel and combat plaque for overall oral health. While not as widely marketed as some modern brands, Pepsodent remains a dependable choice for budget-conscious individuals and families seeking a straightforward, effective toothpaste for everyday use. Its simplicity and focus on core dental care needs make it a long-standing favorite.
20. Biorepair Toothpaste
Biorepair toothpaste focuses on repairing and protecting tooth enamel using innovative microrepair technology. Free from fluoride, it contains hydroxyapatite to strengthen teeth and reduce sensitivity. This toothpaste is ideal for individuals with weakened enamel, sensitivity, or early signs of decay. Its advanced formula addresses specific dental concerns while maintaining overall oral health, making it a strong choice for those seeking specialized care.
21. Attitude Toothpaste
Attitude toothpaste offers a natural, fluoride-free solution for oral hygiene, using plant- and mineral-based ingredients. Free from artificial colors, flavors, and preservatives, it provides cavity protection and freshens breath with gentle, eco-friendly formulas. Perfect for health-conscious consumers, this toothpaste is also vegan and cruelty-free. Attitude appeals to individuals seeking effective, sustainable oral care options focusing on environmental responsibility.
22. Marvis Toothpaste
Marvis toothpaste is renowned for its rich flavors and elegant packaging, offering a unique blend of style and performance. Its fluoride-based formula whitens teeth, protects against cavities, and freshens breath with bold, long-lasting flavors like mint, cinnamon, and licorice. Marvis is an excellent choice for individuals looking for a premium toothpaste that combines effective oral care with an elevated sensory experience.
23. Desert Essence Toothpaste
Desert Essence toothpaste features natural, fluoride-free formulas enriched with tea tree oil, baking soda, and essential oils. Designed for plaque removal and gum care, it’s an ideal choice for individuals seeking natural, chemical-free oral care. Vegan and cruelty-free, Desert Essence products cater to eco-conscious consumers who prioritize sustainable ingredients without sacrificing quality or effectiveness in their dental routine.
Crest Is the Best Toothpaste Brand In America
Through innovative formulations and effective marketing strategies, Crest has established itself as a leading toothpaste brand in the United States. Introduced by Procter & Gamble in 1955, Crest was among the first to incorporate fluoride, significantly contributing to cavity prevention and earning widespread consumer trust. This early adoption of fluoride technology set Crest apart from competitors and laid the foundation for its enduring success.
The brand’s commitment to addressing diverse oral health needs has been pivotal in its rise to prominence. Crest offers a wide range of products, including options for whitening, sensitivity relief, gum health, and enamel strengthening. This extensive product line appeals to a broad consumer base, from individuals seeking cosmetic enhancements to those requiring specialized dental care, thereby enhancing its market reach.
Strategic marketing and collaborations with dental professionals have further solidified Crest’s position in the market. Endorsements from the American Dental Association and consistent recommendations from dentists have reinforced consumer confidence in the brand. Additionally, memorable advertising campaigns have effectively communicated Crest’s benefits, fostering brand loyalty across generations.
Crest’s success can also be attributed to its responsiveness to consumer preferences and market trends. By continuously innovating and expanding its product offerings, Crest has maintained relevance in a competitive market. Its ability to adapt to changing consumer needs and preferences has ensured its sustained leadership in the US toothpaste market.
This pack includes four 3.7 oz tubes of Crest 3D White Advanced Luminous Mint Toothpaste, offering advanced whitening power. Formulated to remove up to 90% more surface stains than regular toothpaste, it helps reveal a brighter, whiter smile. Achieve noticeable whitening results in just five days while benefiting from cavity protection and fresh breath. The refreshing mint flavor enhances your oral care routine, delivering a clean and radiant smile every day.

Share Your Favorite Toothpaste Brands or Suggestions
Your input is important! Sharing your experiences with the toothpaste brands listed—or others you’ve used—helps us improve our content and guide readers toward the most trusted options. Your feedback can highlight what works, offer practical tips, and even introduce readers to new brands. By sharing your thoughts, you contribute to a community focused on making informed choices for better oral health. Thanks for helping others discover the best toothpaste brands and products on the market today! If you enjoyed this listicle, check out our other lists in this category!
